Shareholder FAQ

Q. Who is the transfer agent for Vion Pharmaceuticals, Inc.?
Q. Does Vion Pharmaceuticals, Inc. have a Direct Stock Purchase Program?
Q. What is a record date?
Q. What is a "street name" or beneficial holder?
Q. Who is the contact for Rule 144 opinons?
Q. How do stockholders exchange their shares of Vion common stock as a result of the February 2007 reverse stock split?

Q. Who is the transfer agent for Vion Pharmaceuticals, Inc.?

A: American Stock Transfer & Trust Company (AST) acts as transfer agent for Vion Pharmaceuticals, Inc. In this capacity, AST maintains stockholder records for the company and performs all stock registrations and transfers. AST also handles all stockholder account requests, including change of address and replacement of lost stock certificates, You can contact AST at 1-800-937-5449 or by writing to AST at 59 Maiden Lane, New York, NY 10038.

If you are a beneficial owner (i.e. you hold in "street name"), you should contact your broker rather than AST.

Q. Does Vion Pharmaceuticals, Inc. have a Direct Stock Purchase Program?

A: At this time Vion Pharmaceuticals, Inc. does not have a Direct Stock Purchase Program. Any purchase of the company stock must be made through a bank, broker or other financial institution.

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Q. What is a record date?

A: A record date is the date on which you must be officially listed as a stockholder of a company in order to be eligble to vote at the company's annual meeting.

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Q. What is a "street name" or beneficial holder?

A: Securities held in the name of a broker for the client are said to be carried in "street name." This occurs when the customer wishes the security to be held by the broker.

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Q. Who is the contact for Rule 144 opinions?

A: For Rule 144 opinions, brokers should contact Vion's attorneys by fax or by mail: Fulbright & Jaworski, Attention: Vion Pharmaceuticals, Inc., 666 Fifth Avenue, New York, NY 10103-3198, Fax: 212.318.3400

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Q. How do stockholders exchange their shares of Vion common stock as a result of the February 2007 reverse stock split?

A: On February 20, 2008, Vion effected a one-for-ten reverse stock split of its common stock. As a result of the reverse stock split, every 10 shares of Vion common stock were combined into one share of Von common stock.

If you are a beneficial owner, your shares held electronically through your broker were automatically adjusted for the reverse split. Please contact your broker with any questions on the exchange.

If you are a shareholder of record, a letter of transmittal was mailed in February 2008 to you by American Stock Transfer & Trust Company (AST) with instructions on how to exchange your shares. If you have questions on the exchange process or did not receive a transmittal letter, you may contact AST at 1-800-937-5449.

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We hope we have provided you with answers to some of your questions. If you have a specific question please contact us.