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Products & Pipeline


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Cloretazine® (VNP40101M)
is a novel cytotoxic agent in clinical development for treatment of acute myelogenous leukemia (AML). In addition, clinical trials of Cloretazine® (VNP40101M) are underway in brain tumors in combination with temzolomide and in advanced hematologic malignancies in combination with hematopoietic cell transplantation.

Triapine® is designed to prevent the replication of tumor cells by blocking DNA, an enzyme critical to synthesis and repair. Triapine® is in clinical trials sponsored by the National Cancer Institute.



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Cloretazine® Triapine®